#In #classical #multiple #endocrine #neoplasia #type 2A, #most #patients #develop


A. #medullary #thyroid #cancer.
B. #pheochromocytoma.
C. #primary #hyperparathyroidism.
D. #insulinoma.
E. #pituitary #adenomas

https://twitter.com/DrATEFAHMED/status/1645521771729231873?s=20

ANSWER: A

Multiple endocrine neoplasias (MEN) are autosomal
dominant inherited familial disorders characterizing a
predisposition to tumors of endocrine organs
The tumors include both benign and malignant tumors and
are frequently multicentric. The tumors may arise
synchronously or metachronously. Classical MEN2A
includes medullary thyroid cancer, pheochromocytoma, and
primary hyperparathyroidism. Medullary thyroid cancer and
pheochromocytoma are also seen inMEN2B.
Nearly all patients with classical MEN2A develop medullary
thyroid cancer; fewer patients develop pheochromocytomas
or primary hyperparathyroidism. However,
pheochromocytomas should be excluded whenever a
diagnosis of medullary thyroid cancer is made because
pheochromocytomas should be treated first when any
intervention is planned. Pancreatic neuroendocrine tumors,
pituitary adenomas, and parathyroid hyperplasia are
characteristic of MEN 1.
#In #classical #multiple #endocrine #neoplasia #type 2A, #most #patients #develop A. #medullary #thyroid #cancer. B. #pheochromocytoma. C. #primary #hyperparathyroidism. D. #insulinoma. E. #pituitary #adenomas https://twitter.com/DrATEFAHMED/status/1645521771729231873?s=20 ANSWER: A Multiple endocrine neoplasias (MEN) are autosomal dominant inherited familial disorders characterizing a predisposition to tumors of endocrine organs The tumors include both benign and malignant tumors and are frequently multicentric. The tumors may arise synchronously or metachronously. Classical MEN2A includes medullary thyroid cancer, pheochromocytoma, and primary hyperparathyroidism. Medullary thyroid cancer and pheochromocytoma are also seen inMEN2B. Nearly all patients with classical MEN2A develop medullary thyroid cancer; fewer patients develop pheochromocytomas or primary hyperparathyroidism. However, pheochromocytomas should be excluded whenever a diagnosis of medullary thyroid cancer is made because pheochromocytomas should be treated first when any intervention is planned. Pancreatic neuroendocrine tumors, pituitary adenomas, and parathyroid hyperplasia are characteristic of MEN 1.
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