• #In #classical #multiple #endocrine #neoplasia #type 2A, #most #patients #develop


    A. #medullary #thyroid #cancer.
    B. #pheochromocytoma.
    C. #primary #hyperparathyroidism.
    D. #insulinoma.
    E. #pituitary #adenomas

    https://twitter.com/DrATEFAHMED/status/1645521771729231873?s=20

    ANSWER: A

    Multiple endocrine neoplasias (MEN) are autosomal
    dominant inherited familial disorders characterizing a
    predisposition to tumors of endocrine organs
    The tumors include both benign and malignant tumors and
    are frequently multicentric. The tumors may arise
    synchronously or metachronously. Classical MEN2A
    includes medullary thyroid cancer, pheochromocytoma, and
    primary hyperparathyroidism. Medullary thyroid cancer and
    pheochromocytoma are also seen inMEN2B.
    Nearly all patients with classical MEN2A develop medullary
    thyroid cancer; fewer patients develop pheochromocytomas
    or primary hyperparathyroidism. However,
    pheochromocytomas should be excluded whenever a
    diagnosis of medullary thyroid cancer is made because
    pheochromocytomas should be treated first when any
    intervention is planned. Pancreatic neuroendocrine tumors,
    pituitary adenomas, and parathyroid hyperplasia are
    characteristic of MEN 1.
    #In #classical #multiple #endocrine #neoplasia #type 2A, #most #patients #develop A. #medullary #thyroid #cancer. B. #pheochromocytoma. C. #primary #hyperparathyroidism. D. #insulinoma. E. #pituitary #adenomas https://twitter.com/DrATEFAHMED/status/1645521771729231873?s=20 ANSWER: A Multiple endocrine neoplasias (MEN) are autosomal dominant inherited familial disorders characterizing a predisposition to tumors of endocrine organs The tumors include both benign and malignant tumors and are frequently multicentric. The tumors may arise synchronously or metachronously. Classical MEN2A includes medullary thyroid cancer, pheochromocytoma, and primary hyperparathyroidism. Medullary thyroid cancer and pheochromocytoma are also seen inMEN2B. Nearly all patients with classical MEN2A develop medullary thyroid cancer; fewer patients develop pheochromocytomas or primary hyperparathyroidism. However, pheochromocytomas should be excluded whenever a diagnosis of medullary thyroid cancer is made because pheochromocytomas should be treated first when any intervention is planned. Pancreatic neuroendocrine tumors, pituitary adenomas, and parathyroid hyperplasia are characteristic of MEN 1.
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